Catalytic self-assembly of a DNA dendritic complex for efficient gene silencing.
نویسندگان
چکیده
A catalytic self-assembled DNA dendritic complex was herein reported and used for siRNA-based gene silencing. This kind of one-pot DNA dendrimer can be conveniently prepared as needed, and it was demonstrated to have better silencing efficiency and lower cytotoxicity than commercial cationic lipid transfection agents.
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عنوان ژورنال:
- Chemical communications
دوره 52 7 شماره
صفحات -
تاریخ انتشار 2016